Antibiotic resistant means resistant to current known antibiotics. Is it possible to evolve a bacteria which is resistant to both current and all future antibiotics? (Perhaps within a certain class, e.g., beta lactam.)
My first guess is "no": evolution closing one door of interfering with bacteria function opens another, which can, in principle, be exploited by a future antibiotic. (In practice, it may be prohibitively difficult to discover this antibiotic.)
However, it could be that the new door can only be exploited by compounds extremely toxic to humans.
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